Minor stroke captured on video Watch as it happen
About this video
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# 🧠 **Minor Stroke (TIA / Mild Ischemic Stroke)**
A **minor stroke** means an **ischemic stroke with mild neurological deficits** (often **NIHSS ≤ 5**) OR a **Transient Ischemic Attack (TIA)** where symptoms resolve within **24 hours**.
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# 1️⃣ **Definition**
* **Minor Stroke:** Small ischemic injury causing mild, non-disabling neurological deficit (speech difficulty, limb weakness, facial droop, gait imbalance, visual loss).
* **Transient Ischemic Attack (TIA):** A brief episode of neurological dysfunction caused by focal brain ischemia **without infarction**.
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# 2️⃣ **Pathophysiology**
* **Reduced cerebral blood flow** from vascular occlusion (thrombus or embolus).
* Leads to:
* **Penumbra**: salvageable tissue with reduced perfusion.
* **Core infarct**: irreversible damage if perfusion not restored.
* Mechanisms:
* **Atherosclerosis** → carotid plaque rupture → thrombus.
* **Cardioembolism** (AF, valvular disease).
* **Small vessel (lacunar)** disease (HTN, diabetes).
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# 3️⃣ **Causes & Triggers**
* **Hypertension** (most common risk factor)
* **Diabetes**
* **Atrial fibrillation**
* **Hyperlipidemia**
* **Carotid stenosis**
* **Smoking**
* **Obesity**
* **Sedentary lifestyle**
* **Oral contraceptives**, pregnancy
* **Cocaine, amphetamines**
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# 4️⃣ **Clinical Features**
Symptoms depend on region affected:
### **Cortical (MCA)**
* Facial droop
* Arm weakness
* Aphasia (left)
* Neglect (right)
### **Brainstem**
* Diplopia
* Dysarthria
* Ataxia
### **Cerebellar**
* Vertigo
* Imbalance
* Nystagmus
### **TIA**
* Symptoms resolve within minutes–hours.
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# 5️⃣ **Investigations**
## **Immediate**
* **CT brain (non-contrast)** – rule out hemorrhage.
* **MRI DWI** – detects small infarcts.
* **Blood tests**: CBC, RBS, lipids, INR, renal function.
* **ECG** – AF detection.
## **Further evaluation**
* **Carotid Doppler** – stenosis.
* **Echocardiography** – cardioembolic source.
* **Holter** – paroxysmal AF.
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# 6️⃣ **Differential Diagnosis**
* Migraine aura
* Seizure with post-ictal paralysis (Todd's)
* Hypoglycemia
* Demyelinating disease
* Vestibular neuritis
* Functional neurological disorder
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# 7️⃣ **Management (Stepwise)**
## ⭐ **Immediate Emergency Steps**
1. **ABC stabilization**
2. **Check glucose** → Correct hypoglycemia.
3. **CT scan** immediately.
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## ⭐ **Acute Treatment**
### **If within window (≤ 4.5 hours):**
* **IV Thrombolysis (Alteplase)**
* Dose: **0.9 mg/kg** (max 90 mg)
* 10% bolus in 1 min
* Rest infused over 60 min
### **If large vessel occlusion and NIHSS mild but disabling:**
* **Mechanical thrombectomy** within **6–24 hours** (based on perfusion imaging).
### **If not eligible for thrombolysis:**
* **Dual antiplatelet therapy (DAPT)**
* **Aspirin 81–325 mg** + **Clopidogrel 75 mg**
* **Duration:** 21 days → then single antiplatelet lifelong.
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## ⭐ **Secondary Prevention**
### **Antiplatelets**
* Aspirin 81–325 mg daily
* OR Clopidogrel 75 mg
### **Statins**
* **High-intensity statin:**
* Atorvastatin **40–80 mg**
* Rosuvastatin **20–40 mg**
### **Blood pressure control**
* Goal: **<130/80**
### **Diabetes control**
* HbA1c target: **<7%**
### **Anticoagulation**
If stroke due to **atrial fibrillation**:
* Apixaban 5 mg BID
* Dabigatran 110–150 mg BID
* Rivaroxaban 20 mg daily
(Timing: usually 3–14 days post-stroke depending on size)
### **Lifestyle**
* Smoking cessation
* Weight loss
* Exercise 150 min/week
* DASH/Mediterranean diet
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# 8️⃣ **Complications**
* Recurrent stroke (highest risk in first **48 hours**)
* Long-term disability
* Cognitive decline
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# 9️⃣ **Prognosis**
* Minor stroke has **excellent recovery** if treated early.
* Risk of major stroke after TIA is **10% within 90 days** (half occur in first 48 hours).
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# 🔟 **Patient Counselling**
* Seek emergency care if **any new weakness, slurred speech, facial droop** returns.
* Importance of **adherence to medications**.
* Control BP, sugar, cholesterol strictly.
* Avoid smoking, alcohol excess, and heavy salt.
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